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Urotensin II promotes secretion of LTB(4) through 5-lipoxygenase via the UT-ROS-Akt pathway in RAW264.7 macrophages

INTRODUCTION: Urotensin II (UII) is an important vasoactive peptide involved in the pathogenesis of atherosclerosis. Monocytes/macrophages play important roles in every step of atherosclerosis. Although UII has a chemoattractant effect on monocytes, it is unclear whether UII regulates inflammatory r...

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Detalles Bibliográficos
Autores principales: Lu, Dan, Peng, Fen, Li, Jun, Zhao, Jing, Ye, Xiaojin, Li, Binghan, Ding, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657259/
https://www.ncbi.nlm.nih.gov/pubmed/31360201
http://dx.doi.org/10.5114/aoms.2019.85197