Cargando…

Modeling breast cancer progression to bone: how driver mutation order and metabolism matter

BACKGROUND: Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the occurrence of very few driver mutations promoting oncogenic cell behaviours. Usua...

Descripción completa

Detalles Bibliográficos
Autores principales: Ascolani, Gianluca, Liò, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657267/
https://www.ncbi.nlm.nih.gov/pubmed/31345216
http://dx.doi.org/10.1186/s12920-019-0541-4