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Modeling breast cancer progression to bone: how driver mutation order and metabolism matter
BACKGROUND: Not all the mutations are equally important for the development of metastasis. What about their order? The survival of cancer cells from the primary tumour site to the secondary seeding sites depends on the occurrence of very few driver mutations promoting oncogenic cell behaviours. Usua...
Autores principales: | Ascolani, Gianluca, Liò, Pietro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657267/ https://www.ncbi.nlm.nih.gov/pubmed/31345216 http://dx.doi.org/10.1186/s12920-019-0541-4 |
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