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Prediction and interpretation of miRNA-disease associations based on miRNA target genes using canonical correlation analysis
BACKGROUND: It has been shown that the deregulation of miRNAs is associated with the development and progression of many human diseases. To reduce time and cost of biological experiments, a number of algorithms have been proposed for predicting miRNA-disease associations. However, the existing metho...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657378/ https://www.ncbi.nlm.nih.gov/pubmed/31345171 http://dx.doi.org/10.1186/s12859-019-2998-8 |