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Prediction and interpretation of miRNA-disease associations based on miRNA target genes using canonical correlation analysis

BACKGROUND: It has been shown that the deregulation of miRNAs is associated with the development and progression of many human diseases. To reduce time and cost of biological experiments, a number of algorithms have been proposed for predicting miRNA-disease associations. However, the existing metho...

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Detalles Bibliográficos
Autores principales: Chen, Hailin, Zhang, Zuping, Feng, Dayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657378/
https://www.ncbi.nlm.nih.gov/pubmed/31345171
http://dx.doi.org/10.1186/s12859-019-2998-8