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Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of dementia. The onset and progression of this pathology are correlated with several changes in the brain, including the formation of extracellular aggregates of amyloid-beta (Aβ) peptide and the intracellular accumulation of hyperphosphorylated tau p...

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Detalles Bibliográficos
Autores principales: Cisternas, Pedro, Oliva, Carolina A., Torres, Viviana I., Barrera, Daniela P., Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657419/
https://www.ncbi.nlm.nih.gov/pubmed/31379502
http://dx.doi.org/10.3389/fncel.2019.00295