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Combination Therapy with Disulfiram, Copper, and Doxorubicin for Osteosarcoma: In Vitro Support for a Novel Drug Repurposing Strategy

Although many cancer cells have significantly higher copper concentrations compared with normal cells and tissues, the role of copper in cancer biology and metastatic disease remains poorly understood. Here, we study the importance of copper in osteosarcoma, which frequently metastasizes to the lung...

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Detalles Bibliográficos
Autores principales: Mandell, Jonathan B., Lu, Feiqi, Fisch, Matthew, Beumer, Jan H., Guo, Jianxia, Watters, Rebecca J., Weiss, Kurt R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657614/
https://www.ncbi.nlm.nih.gov/pubmed/31379466
http://dx.doi.org/10.1155/2019/1320201