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Histone Arginine Methylation-Mediated Epigenetic Regulation of Discoidin Domain Receptor 2 Controls the Senescence of Human Bone Marrow Mesenchymal Stem Cells

The application of human bone marrow mesenchymal stem cells (hBM-MSCs) in cell-based clinical therapies is hindered by the limited number of cells remaining after the initial isolation process and by cellular senescence following in vitro expansion. Understanding the process of in vitro senescence i...

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Detalles Bibliográficos
Autores principales: Xu, Zhenyu, Wu, Wenming, Shen, Fang, Yu, Yue, Wang, Yue, Xiang, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657615/
https://www.ncbi.nlm.nih.gov/pubmed/31379950
http://dx.doi.org/10.1155/2019/7670316