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Histone Arginine Methylation-Mediated Epigenetic Regulation of Discoidin Domain Receptor 2 Controls the Senescence of Human Bone Marrow Mesenchymal Stem Cells
The application of human bone marrow mesenchymal stem cells (hBM-MSCs) in cell-based clinical therapies is hindered by the limited number of cells remaining after the initial isolation process and by cellular senescence following in vitro expansion. Understanding the process of in vitro senescence i...
Autores principales: | Xu, Zhenyu, Wu, Wenming, Shen, Fang, Yu, Yue, Wang, Yue, Xiang, Charlie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657615/ https://www.ncbi.nlm.nih.gov/pubmed/31379950 http://dx.doi.org/10.1155/2019/7670316 |
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