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Signaling Through gp130 Compromises Suppressive Function in Human FOXP3(+) Regulatory T Cells

The CD4(+)FOXP3(+) regulatory T cell (Treg) subset is an indispensable mediator of immune tolerance. While high and stable expression of the transcription factor FOXP3 is considered a hallmark feature of Treg cells, our previous studies have demonstrated that the human FOXP3(+) subset is functionall...

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Detalles Bibliográficos
Autores principales: Bin Dhuban, Khalid, Bartolucci, Sabrina, d'Hennezel, Eva, Piccirillo, Ciriaco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657659/
https://www.ncbi.nlm.nih.gov/pubmed/31379810
http://dx.doi.org/10.3389/fimmu.2019.01532