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Signaling Through gp130 Compromises Suppressive Function in Human FOXP3(+) Regulatory T Cells
The CD4(+)FOXP3(+) regulatory T cell (Treg) subset is an indispensable mediator of immune tolerance. While high and stable expression of the transcription factor FOXP3 is considered a hallmark feature of Treg cells, our previous studies have demonstrated that the human FOXP3(+) subset is functionall...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657659/ https://www.ncbi.nlm.nih.gov/pubmed/31379810 http://dx.doi.org/10.3389/fimmu.2019.01532 |