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Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations
Multidrug-resistant clinical isolates are common in certain pathogens, but rare in others. This pattern may be due to the fact that mutations shaping resistance have species-specific effects. To investigate this issue, we transferred a range of resistance-conferring mutations and a full resistance g...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657729/ https://www.ncbi.nlm.nih.gov/pubmed/31058961 http://dx.doi.org/10.1093/molbev/msz109 |