A system for site-specific integration of transgenes in mammalian cells

Mammalian cell expression systems are the most commonly used platforms for producing biotherapeutic proteins. However, development of recombinant mammalian cell lines is often hindered by the unstable and variable transgene expression associated with random integration. We have developed an efficien...

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Detalles Bibliográficos
Autores principales: Chi, Xiuling, Zheng, Qi, Jiang, Ruhong, Chen-Tsai, Ruby Yanru, Kong, Ling-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657834/
https://www.ncbi.nlm.nih.gov/pubmed/31344144
http://dx.doi.org/10.1371/journal.pone.0219842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657834/
https://www.ncbi.nlm.nih.gov/pubmed/31344144
http://dx.doi.org/10.1371/journal.pone.0219842

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