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A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells

BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are used to treat autoimmune or inflammatory diseases. Our aim was to determine the immunomodulatory mechanisms elicited by MSCs during inflammation. METHODS AND RESULTS: We cocultured MSCs with peripheral blood mononuclear cells for a mixed l...

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Detalles Bibliográficos
Autores principales: Yi, Tac-Ghee, Cho, Yun-Kyoung, Lee, Hyun-Joo, Kim, Junghee, Jeon, Myung-Shin, Ham, Dong-Sik, Kim, Woo Cheol, Song, Sun U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657938/
https://www.ncbi.nlm.nih.gov/pubmed/31242717
http://dx.doi.org/10.15283/ijsc18098