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SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders

Peroxisomal disorders are genetically heterogeneous metabolic disorders associated with a deficit of very long chain fatty acid β-oxidation that commonly manifest as early-onset neurodegeneration. Brain microvascular endothelial dysfunction with increased permeability to monocytes has been described...

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Detalles Bibliográficos
Autores principales: Zhang, Yunshan, Cui, Guiyun, Wang, Yue, Gong, Yi, Wang, Yulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657955/
https://www.ncbi.nlm.nih.gov/pubmed/31257461
http://dx.doi.org/10.3892/ijmm.2019.4250