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SIRT1 activation alleviates brain microvascular endothelial dysfunction in peroxisomal disorders
Peroxisomal disorders are genetically heterogeneous metabolic disorders associated with a deficit of very long chain fatty acid β-oxidation that commonly manifest as early-onset neurodegeneration. Brain microvascular endothelial dysfunction with increased permeability to monocytes has been described...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657955/ https://www.ncbi.nlm.nih.gov/pubmed/31257461 http://dx.doi.org/10.3892/ijmm.2019.4250 |