Gas6 attenuates lipopolysaccharide-induced TNF-α expression and apoptosis in H9C2 cells through NF-κB and MAPK inhibition via the Axl/PI3K/Akt pathway

Therapeutic agents used to treat sepsis-induced cardiac dysfunction are designed to suppress tumor necrosis factor (TNF)-α release and inhibit cell apoptosis. Exogenous administration of growth arrest-specific 6 (Gas6) exerts several biological and pharmacological effects; however, the role of Gas6...

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Detalles Bibliográficos
Autores principales: Li, Mengfang, Ye, Jingjing, Zhao, Guangju, Hong, Guangliang, Hu, Xiyi, Cao, Kaiqiang, Wu, You, Lu, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657963/
https://www.ncbi.nlm.nih.gov/pubmed/31524235
http://dx.doi.org/10.3892/ijmm.2019.4275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657963/
https://www.ncbi.nlm.nih.gov/pubmed/31524235
http://dx.doi.org/10.3892/ijmm.2019.4275

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