Cargando…

Epigenetic regulation of COX-2 expression by DNA hypomethylation via NF-κB activation in ketamine-induced ulcerative cystitis

The present study investigated the methylation of CpG sites in the cyclooxygenase (COX)-2 promoter via nuclear factor (NF)-κB transcriptional regulation and elucidated its effect on the COX-2 transcriptional expression in a ketamine-induced ulcerative cystitis (KIC) animal model. The results of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Chuang, Shu-Mien, Lu, Jian-He, Lin, Kun-Ling, Long, Cheng-Yu, Lee, Yung-Chin, Hsiao, Hui-Pin, Tsai, Chia-Chun, Wu, Wen-Jeng, Yang, Hui-Jun, Juan, Yung-Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657979/
https://www.ncbi.nlm.nih.gov/pubmed/31257475
http://dx.doi.org/10.3892/ijmm.2019.4252