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Epigenetic regulation of COX-2 expression by DNA hypomethylation via NF-κB activation in ketamine-induced ulcerative cystitis
The present study investigated the methylation of CpG sites in the cyclooxygenase (COX)-2 promoter via nuclear factor (NF)-κB transcriptional regulation and elucidated its effect on the COX-2 transcriptional expression in a ketamine-induced ulcerative cystitis (KIC) animal model. The results of the...
Autores principales: | Chuang, Shu-Mien, Lu, Jian-He, Lin, Kun-Ling, Long, Cheng-Yu, Lee, Yung-Chin, Hsiao, Hui-Pin, Tsai, Chia-Chun, Wu, Wen-Jeng, Yang, Hui-Jun, Juan, Yung-Shun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657979/ https://www.ncbi.nlm.nih.gov/pubmed/31257475 http://dx.doi.org/10.3892/ijmm.2019.4252 |
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