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Micro-dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture

Primary human hepatocytes (PHHs) are the gold standard for drug development procedures; however, maintaining functional PHHs in vitro is challenging in conventional collagen-coated cultures. In the present study, we developed a new scaffold comprising high amounts (≥1 mg/cm(2)) of atelocollagen expo...

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Detalles Bibliográficos
Autores principales: Sato, Tetsuro, Semura, Kayoko, Fujimoto, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657980/
https://www.ncbi.nlm.nih.gov/pubmed/31257473
http://dx.doi.org/10.3892/ijmm.2019.4251