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Micro-dimpled surface atelocollagen maintains primary human hepatocytes in culture and may promote their functionality compared with collagen coat culture
Primary human hepatocytes (PHHs) are the gold standard for drug development procedures; however, maintaining functional PHHs in vitro is challenging in conventional collagen-coated cultures. In the present study, we developed a new scaffold comprising high amounts (≥1 mg/cm(2)) of atelocollagen expo...
Autores principales: | Sato, Tetsuro, Semura, Kayoko, Fujimoto, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657980/ https://www.ncbi.nlm.nih.gov/pubmed/31257473 http://dx.doi.org/10.3892/ijmm.2019.4251 |
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