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A cell-loss-free concave microwell array based size-controlled multi-cellular tumoroid generation for anti-cancer drug screening

The 3D multi-cellular tumoroid (MCT) model is an in vivo-like, avascular tumor model that has received much attention as a refined screening platform for drug therapies. Several types of research have been efforted to improve the physiological characteristics of the tumor microenvironment (TME) of t...

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Detalles Bibliográficos
Autores principales: Lee, Sang Woo, Jeong, Soo Yeon, Shin, Tae Hoon, Min, Junhong, Lee, Donghyun, Jeong, Gi Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658056/
https://www.ncbi.nlm.nih.gov/pubmed/31344058
http://dx.doi.org/10.1371/journal.pone.0219834