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Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP‐1

OBJECTIVE: A previous genome‐wide association study linked overexpression of an ATP‐binding cassette transporter, ABCC5, in humans with a susceptibility to developing type 2 diabetes with age. Specifically, ABCC5 gene overexpression was shown to be strongly associated with increased visceral fat mas...

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Detalles Bibliográficos
Autores principales: Cyranka, Malgorzata, Veprik, Anna, McKay, Eleanor J., van Loon, Nienke, Thijsse, Amber, Cotter, Luke, Hare, Nisha, Saibudeen, Affan, Lingam, Swathi, Pires, Elisabete, Larraufie, Pierre, Reimann, Frank, Gribble, Fiona, Stewart, Michelle, Bentley, Elizabeth, Lear, Pamela, McCullagh, James, Cantley, James, Cox, Roger D., de Wet, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658130/
https://www.ncbi.nlm.nih.gov/pubmed/31338999
http://dx.doi.org/10.1002/oby.22521