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GRP78 translocation to the cell surface and O-GlcNAcylation of VE-Cadherin contribute to ER stress-mediated endothelial permeability
Increased O-GlcNAcylation, a well-known post-translational modification of proteins causally linked to various detrimental cellular functions in pathological conditions including diabetic retinopathy (DR). Previously we have shown that endothelial activation induced by inflammation and hyperglycemia...
Autores principales: | Lenin, Raji, Nagy, Peter G., Jha, Kumar Abhiram, Gangaraju, Rajashekhar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658495/ https://www.ncbi.nlm.nih.gov/pubmed/31346222 http://dx.doi.org/10.1038/s41598-019-47246-w |
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