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Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons

Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary mammalian cells on both the RNA and protein levels. These cells offer unique opportunities, including insights into mechanistic understandin...

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Detalles Bibliográficos
Autores principales: Moakley, Daniel, Koh, Joan, Pereira, Joao D., DuBreuil, Daniel M., Devlin, Anna-Claire, Berezovski, Eugene, Zhu, Kevin, Wainger, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658502/
https://www.ncbi.nlm.nih.gov/pubmed/31346219
http://dx.doi.org/10.1038/s41598-019-47203-7