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Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons
Directed differentiation of human pluripotent stem cells (hPSCs) has enabled the generation of specific neuronal subtypes that approximate the intended primary mammalian cells on both the RNA and protein levels. These cells offer unique opportunities, including insights into mechanistic understandin...
Autores principales: | Moakley, Daniel, Koh, Joan, Pereira, Joao D., DuBreuil, Daniel M., Devlin, Anna-Claire, Berezovski, Eugene, Zhu, Kevin, Wainger, Brian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658502/ https://www.ncbi.nlm.nih.gov/pubmed/31346219 http://dx.doi.org/10.1038/s41598-019-47203-7 |
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