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MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins

Channelrhodopsins (ChRs) are algal light-gated ion channels widely used as optogenetic tools for manipulating neuronal activity. ChRs desensitize under continuous bright-light illumination, resulting in a significant decline of photocurrents. Here we describe a metagenomically identified family of p...

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Detalles Bibliográficos
Autores principales: Oppermann, Johannes, Fischer, Paul, Silapetere, Arita, Liepe, Bernhard, Rodriguez-Rozada, Silvia, Flores-Uribe, José, Peter, Enrico, Keidel, Anke, Vierock, Johannes, Kaufmann, Joel, Broser, Matthias, Luck, Meike, Bartl, Franz, Hildebrandt, Peter, Wiegert, J. Simon, Béjà, Oded, Hegemann, Peter, Wietek, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658528/
https://www.ncbi.nlm.nih.gov/pubmed/31346176
http://dx.doi.org/10.1038/s41467-019-11322-6