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Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling

ORAI1 Ca(2+) channels in the plasma membrane (PM) are gated by STIM1 at endoplasmic reticulum (ER)-PM junctions to effect store-dependent Ca(2+) entry into cells, but little is known about how local STIM-ORAI signalling at junctions is coordinated with overall cellular architecture. Filamentous sept...

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Detalles Bibliográficos
Autores principales: Katz, Zachary B., Zhang, Chen, Quintana, Ariel, Lillemeier, Björn F., Hogan, Patrick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658532/
https://www.ncbi.nlm.nih.gov/pubmed/31346209
http://dx.doi.org/10.1038/s41598-019-46862-w