Cargando…
Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling
ORAI1 Ca(2+) channels in the plasma membrane (PM) are gated by STIM1 at endoplasmic reticulum (ER)-PM junctions to effect store-dependent Ca(2+) entry into cells, but little is known about how local STIM-ORAI signalling at junctions is coordinated with overall cellular architecture. Filamentous sept...
Autores principales: | Katz, Zachary B., Zhang, Chen, Quintana, Ariel, Lillemeier, Björn F., Hogan, Patrick G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658532/ https://www.ncbi.nlm.nih.gov/pubmed/31346209 http://dx.doi.org/10.1038/s41598-019-46862-w |
Ejemplares similares
-
Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum–plasma membrane junctions
por: Wu, Minnie M., et al.
Publicado: (2014) -
STIM1 triggers a gating rearrangement at the extracellular mouth of the ORAI1 channel
por: Gudlur, Aparna, et al.
Publicado: (2014) -
STIM1–Orai1 Interaction Exacerbates LPS-Induced Inflammation and Endoplasmic Reticulum Stress in Bovine Hepatocytes through Store-Operated Calcium Entry
por: Xue, Yang, et al.
Publicado: (2022) -
STIM and Orai1 Variants in Store-Operated Calcium Entry
por: Rosado, Juan A., et al.
Publicado: (2016) -
Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines
por: Zheng, Sisi, et al.
Publicado: (2018)