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AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

The study of primary glucagon-secreting α-cells is hampered by their low abundance and scattered distribution in rodent pancreatic islets. We have designed a double-stranded adeno-associated virus containing a rat proglucagon promoter (700 bp) driving enhanced green fluorescent protein (AAV GCG-EGFP...

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Detalles Bibliográficos
Autores principales: Tudurí, Eva, Glavas, Maria M., Asadi, Ali, Baker, Robert K., Ellis, Cara E., Soukhatcheva, Galina, Philit, Marjolaine, Huynh, Frank K., Johnson, James D., Bruce Verchere, C., Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658537/
https://www.ncbi.nlm.nih.gov/pubmed/31346189
http://dx.doi.org/10.1038/s41598-019-46735-2