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HER2/HER3 regulates lactate secretion and expression of lactate receptor mRNA through the MAP3K4 associated protein GIT1

One of the major features of cancer is Otto Warburg’s observation that many tumors have increased extracellular acidification compared to healthy tissues. Since Warburg’s observation, the importance of extracellular acidification in cancer is now considered a hallmark of cancer. Human MAP3K4 functio...

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Detalles Bibliográficos
Autores principales: Garcia-Flores, Alejandro E., Sollome, James J., Thavathiru, Elangovan, Bower, Joseph L., Vaillancourt, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658559/
https://www.ncbi.nlm.nih.gov/pubmed/31346208
http://dx.doi.org/10.1038/s41598-019-46954-7