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KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants

Most manipulations that extend lifespan also increase resistance to various stress factors and environmental cues in a range of animals from yeast to mammals. However, the underlying molecular mechanisms regulating stress resistance during aging are still largely unknown. Here we identify Krüppel-li...

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Detalles Bibliográficos
Autores principales: Herholz, Marija, Cepeda, Estela, Baumann, Linda, Kukat, Alexandra, Hermeling, Johannes, Maciej, Sarah, Szczepanowska, Karolina, Pavlenko, Victor, Frommolt, Peter, Trifunovic, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658563/
https://www.ncbi.nlm.nih.gov/pubmed/31346165
http://dx.doi.org/10.1038/s41467-019-11275-w