Cargando…
KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants
Most manipulations that extend lifespan also increase resistance to various stress factors and environmental cues in a range of animals from yeast to mammals. However, the underlying molecular mechanisms regulating stress resistance during aging are still largely unknown. Here we identify Krüppel-li...
Autores principales: | Herholz, Marija, Cepeda, Estela, Baumann, Linda, Kukat, Alexandra, Hermeling, Johannes, Maciej, Sarah, Szczepanowska, Karolina, Pavlenko, Victor, Frommolt, Peter, Trifunovic, Aleksandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658563/ https://www.ncbi.nlm.nih.gov/pubmed/31346165 http://dx.doi.org/10.1038/s41467-019-11275-w |
Ejemplares similares
-
Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans
por: Hermeling, Johannes CW, et al.
Publicado: (2022) -
The gut microbiome: an orchestrator of xenobiotic metabolism
por: Collins, Stephanie L., et al.
Publicado: (2020) -
The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis
por: Hofsetz, Eduard, et al.
Publicado: (2020) -
The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway
por: Sáenz Robles, Maria Teresa, et al.
Publicado: (2011) -
Succinate Dehydrogenase Upregulation Destabilize Complex I and Limits the Lifespan of gas-1 Mutant
por: Pujol, Claire, et al.
Publicado: (2013)