Glycine, serine and threonine metabolism confounds efficacy of complement-mediated killing

Serum resistance is a poorly understood but common trait of some difficult-to-treat pathogenic strains of bacteria. Here, we report that glycine, serine and threonine catabolic pathway is down-regulated in serum-resistant Escherichia coli, whereas exogenous glycine reverts the serum resistance and e...

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Detalles Bibliográficos
Autores principales: Cheng, Zhi-xue, Guo, Chang, Chen, Zhuang-gui, Yang, Tian-ci, Zhang, Jian-ying, Wang, Jie, Zhu, Jia-xin, Li, Dan, Zhang, Tian-tuo, Li, Hui, Peng, Bo, Peng, Xuan-xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658569/
https://www.ncbi.nlm.nih.gov/pubmed/31346171
http://dx.doi.org/10.1038/s41467-019-11129-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658569/
https://www.ncbi.nlm.nih.gov/pubmed/31346171
http://dx.doi.org/10.1038/s41467-019-11129-5

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