Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture

Epidermal homeostasis depends on a balance between self-renewal of stem cells and terminal differentiation of their progeny. Notch signalling is known to play a role in epidermal  stem cell patterning and differentiation. However, the molecular mechanisms are incompletely understood. Here we demonst...

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Detalles Bibliográficos
Autores principales: Negri, Victor A., Logtenberg, Meike E. W., Renz, Lisa M., Oules, Bénédicte, Walko, Gernot, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658703/
https://www.ncbi.nlm.nih.gov/pubmed/31346203
http://dx.doi.org/10.1038/s41598-019-47232-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658703/
https://www.ncbi.nlm.nih.gov/pubmed/31346203
http://dx.doi.org/10.1038/s41598-019-47232-2

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