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Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture
Epidermal homeostasis depends on a balance between self-renewal of stem cells and terminal differentiation of their progeny. Notch signalling is known to play a role in epidermal stem cell patterning and differentiation. However, the molecular mechanisms are incompletely understood. Here we demonst...
Autores principales: | Negri, Victor A., Logtenberg, Meike E. W., Renz, Lisa M., Oules, Bénédicte, Walko, Gernot, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658703/ https://www.ncbi.nlm.nih.gov/pubmed/31346203 http://dx.doi.org/10.1038/s41598-019-47232-2 |
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