Cargando…

Essential Role for the Phosphatidylinositol 3,5-Bisphosphate Synthesis Complex in Caspofungin Tolerance and Virulence in Candida glabrata

Increasing resistance of the human opportunistic fungal pathogen Candida glabrata toward the echinocandin antifungals, which target the cell wall, is a matter of grave clinical concern. Echinocandin resistance in C. glabrata has primarily been associated with mutations in the β-glucan synthase-encod...

Descripción completa

Detalles Bibliográficos
Autores principales: Choudhary, Deepak Kumar, Bhakt, Priyanka, Kaur, Rupinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658794/
https://www.ncbi.nlm.nih.gov/pubmed/31138567
http://dx.doi.org/10.1128/AAC.00886-19