Comparison of Different Liver Test Thresholds for Drug-Induced Liver Injury: Updated RUCAM versus Other Methods

According to the updated Roussel Uclaf Causality Assessment Method (RUCAM), drug-induced liver injury (DILI) is currently defined based on thresholds of alanine aminotransferase (ALT) levels above 5 × the upper limit of normal (ULN) and/or alkaline phosphatase (ALP) levels greater than 2 × the ULN....

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Hongyi, Guo, Daihong, Xu, Yuanjie, Zhu, Man, Yao, Chong, Chen, Chao, Jia, Wangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658872/
https://www.ncbi.nlm.nih.gov/pubmed/31379581
http://dx.doi.org/10.3389/fphar.2019.00816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658872/
https://www.ncbi.nlm.nih.gov/pubmed/31379581
http://dx.doi.org/10.3389/fphar.2019.00816

Ejemplares similares