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Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma

Background: Adrenocortical carcinoma (ACC) is a rare tumor entity with restricted therapeutic opportunities. HSP90 (Heat Shock Protein 90) chaperone activity is fundamental for cell survival and contributes to different oncogenic signaling pathways. Indeed, agents targeting HSP90 function have shown...

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Detalles Bibliográficos
Autores principales: Siebert, Claudia, Ciato, Denis, Murakami, Masanori, Frei-Stuber, Ludwig, Perez-Rivas, Luis Gustavo, Monteserin-Garcia, José Luis, Nölting, Svenja, Maurer, Julian, Feuchtinger, Annette, Walch, Axel K., Haak, Harm R., Bertherat, Jérôme, Mannelli, Massimo, Fassnacht, Martin, Korpershoek, Esther, Reincke, Martin, Stalla, Günter K., Hantel, Constanze, Beuschlein, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658895/
https://www.ncbi.nlm.nih.gov/pubmed/31379752
http://dx.doi.org/10.3389/fendo.2019.00487