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Heat Shock Protein 90 as a Prognostic Marker and Therapeutic Target for Adrenocortical Carcinoma
Background: Adrenocortical carcinoma (ACC) is a rare tumor entity with restricted therapeutic opportunities. HSP90 (Heat Shock Protein 90) chaperone activity is fundamental for cell survival and contributes to different oncogenic signaling pathways. Indeed, agents targeting HSP90 function have shown...
Autores principales: | Siebert, Claudia, Ciato, Denis, Murakami, Masanori, Frei-Stuber, Ludwig, Perez-Rivas, Luis Gustavo, Monteserin-Garcia, José Luis, Nölting, Svenja, Maurer, Julian, Feuchtinger, Annette, Walch, Axel K., Haak, Harm R., Bertherat, Jérôme, Mannelli, Massimo, Fassnacht, Martin, Korpershoek, Esther, Reincke, Martin, Stalla, Günter K., Hantel, Constanze, Beuschlein, Felix |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658895/ https://www.ncbi.nlm.nih.gov/pubmed/31379752 http://dx.doi.org/10.3389/fendo.2019.00487 |
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