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Does Natural Killer Cell Deficiency (NKD) Increase the Risk of Cancer? NKD May Increase the Risk of Some Virus Induced Cancer

Natural killer cell deficiency (NKD) is a primary immunodeficiency where the main defect lies in CD56(+)CD3(−) natural killer (NK) cells which mediate cytotoxicity against tumors. Most cases are observed in children and adolescents with recurrent viral infections and cancer. GATA2 and MCM4 mutations...

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Detalles Bibliográficos
Autores principales: Moon, Won Young, Powis, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658984/
https://www.ncbi.nlm.nih.gov/pubmed/31379882
http://dx.doi.org/10.3389/fimmu.2019.01703