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Does Natural Killer Cell Deficiency (NKD) Increase the Risk of Cancer? NKD May Increase the Risk of Some Virus Induced Cancer
Natural killer cell deficiency (NKD) is a primary immunodeficiency where the main defect lies in CD56(+)CD3(−) natural killer (NK) cells which mediate cytotoxicity against tumors. Most cases are observed in children and adolescents with recurrent viral infections and cancer. GATA2 and MCM4 mutations...
Autores principales: | Moon, Won Young, Powis, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658984/ https://www.ncbi.nlm.nih.gov/pubmed/31379882 http://dx.doi.org/10.3389/fimmu.2019.01703 |
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