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Sphingosine-1-Phosphate and Macrophage Biology—How the Sphinx Tames the Big Eater
The sphingolipid sphingosine-1-phosphate (S1P) is produced by sphingosine kinases to either signal through intracellular targets or to activate a family of specific G-protein-coupled receptors (S1PR). S1P levels are usually low in peripheral tissues compared to the vasculature, forming a gradient th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658986/ https://www.ncbi.nlm.nih.gov/pubmed/31379883 http://dx.doi.org/10.3389/fimmu.2019.01706 |