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Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System

Utricular hair cells (HCs) are mechanoreceptors required for vestibular function. After damage, regeneration of mammalian utricular HCs is limited and regenerated HCs appear immature. Thus, loss of vestibular function is presumed irreversible. Here, we found partial HC replacement and functional rec...

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Detalles Bibliográficos
Autores principales: Sayyid, Zahra N., Wang, Tian, Chen, Leon, Jones, Sherri M., Cheng, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659123/
https://www.ncbi.nlm.nih.gov/pubmed/31291569
http://dx.doi.org/10.1016/j.celrep.2019.06.028