Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity

Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced hepatotoxicity is one of the most severe adverse reaction that can lead to death. The objective of this study was to gain an understanding of dysregulated lipid metabolism in mechanism of hepatotoxicity. Non...

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Detalles Bibliográficos
Autores principales: Xu, Shansen, Chen, Yanan, Ma, Yiyi, Liu, Ting, Zhao, Mingming, Wang, Zhanyou, Zhao, Limei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659130/
https://www.ncbi.nlm.nih.gov/pubmed/31379584
http://dx.doi.org/10.3389/fphar.2019.00819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659130/
https://www.ncbi.nlm.nih.gov/pubmed/31379584
http://dx.doi.org/10.3389/fphar.2019.00819

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