Cargando…
Lipidomic Profiling Reveals Disruption of Lipid Metabolism in Valproic Acid-Induced Hepatotoxicity
Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs, as VPA-induced hepatotoxicity is one of the most severe adverse reaction that can lead to death. The objective of this study was to gain an understanding of dysregulated lipid metabolism in mechanism of hepatotoxicity. Non...
Autores principales: | Xu, Shansen, Chen, Yanan, Ma, Yiyi, Liu, Ting, Zhao, Mingming, Wang, Zhanyou, Zhao, Limei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659130/ https://www.ncbi.nlm.nih.gov/pubmed/31379584 http://dx.doi.org/10.3389/fphar.2019.00819 |
Ejemplares similares
-
The serum acylcarnitines profile in epileptic children treated with valproic acid and the protective roles of peroxisome proliferator-activated receptor a activation in valproic acid-induced liver injury
por: Ma, Yiyi, et al.
Publicado: (2022) -
Lipidomics Indicates the Hepatotoxicity Effects of EtOAc Extract of Rhizoma Paridis
por: Li, Chaofeng, et al.
Publicado: (2022) -
Metabolomics and Lipidomics Reveal the Effect of Hepatic Vps33b Deficiency on Bile Acids and Lipids Metabolism
por: Fu, Kaili, et al.
Publicado: (2019) -
HR-MS Based Untargeted Lipidomics Reveals Characteristic Lipid Signatures of Wilson’s Disease
por: Zhi, Yixiao, et al.
Publicado: (2021) -
Assessing hepatotoxicity of valproic acid in Dictyostelium
Publicado: (2012)