Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice

BACKGROUND: Current human influenza vaccines lack the adaptability to match the mutational rate of the virus and therefore require annual revisions. Because of extensive manufacturing times and the possibility that antigenic alterations occur during viral vaccine strain production, an inherent risk...

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Detalles Bibliográficos
Autores principales: Joe, Patrick Tjok, Christopoulou, Ioanna, van Hoecke, Lien, Schepens, Bert, Ysenbaert, Tine, Heirman, Carlo, Thielemans, Kris, Saelens, Xavier, Aerts, Joeri L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659201/
https://www.ncbi.nlm.nih.gov/pubmed/31345237
http://dx.doi.org/10.1186/s12967-019-1991-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659201/
https://www.ncbi.nlm.nih.gov/pubmed/31345237
http://dx.doi.org/10.1186/s12967-019-1991-3

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