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Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice
BACKGROUND: Current human influenza vaccines lack the adaptability to match the mutational rate of the virus and therefore require annual revisions. Because of extensive manufacturing times and the possibility that antigenic alterations occur during viral vaccine strain production, an inherent risk...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659201/ https://www.ncbi.nlm.nih.gov/pubmed/31345237 http://dx.doi.org/10.1186/s12967-019-1991-3 |