Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression

Soluble aggregates of amyloid-β (Aβ) have been associated with neuronal and synaptic loss in Alzheimer’s disease (AD). However, despite significant recent progress, the mechanisms by which these aggregated species contribute to disease progression are not fully determined. As the analysis of human c...

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Detalles Bibliográficos
Autores principales: De, Suman, Whiten, Daniel R., Ruggeri, Francesco S., Hughes, Craig, Rodrigues, Margarida, Sideris, Dimitrios I., Taylor, Christopher G., Aprile, Francesco A., Muyldermans, Serge, Knowles, Tuomas P. J., Vendruscolo, Michele, Bryant, Clare, Blennow, Kaj, Skoog, Ingmar, Kern, Silke, Zetterberg, Henrik, Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659275/
https://www.ncbi.nlm.nih.gov/pubmed/31349874
http://dx.doi.org/10.1186/s40478-019-0777-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659275/
https://www.ncbi.nlm.nih.gov/pubmed/31349874
http://dx.doi.org/10.1186/s40478-019-0777-4

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