RaPID: ultra-fast, powerful, and accurate detection of segments identical by descent (IBD) in biobank-scale cohorts

While genetic relatedness, usually manifested as segments identical by descent (IBD), is ubiquitous in modern large biobanks, current IBD detection methods are not efficient at such a scale. Here, we describe an efficient method, RaPID, for detecting IBD segments in a panel with phased haplotypes. R...

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Detalles Bibliográficos
Autores principales: Naseri, Ardalan, Liu, Xiaoming, Tang, Kecong, Zhang, Shaojie, Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659282/
https://www.ncbi.nlm.nih.gov/pubmed/31345249
http://dx.doi.org/10.1186/s13059-019-1754-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659282/
https://www.ncbi.nlm.nih.gov/pubmed/31345249
http://dx.doi.org/10.1186/s13059-019-1754-8

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