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SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways

BACKGROUND: The SUMO-activating enzyme SAE1 is indispensable for protein SUMOylation. A dysregulation of SAE1 expression involves in progression of several human cancers. However, its biological roles of SAE1 in glioma are unclear by now. METHODS: The differential proteome between human glioma tissu...

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Detalles Bibliográficos
Autores principales: Yang, Yanfang, Liang, Ziwei, Xia, Zijing, Wang, Xixi, Ma, Yanni, Sheng, Zenghua, Gu, Qingjia, Shen, Guobo, Zhou, Liangxue, Zhu, Hongxia, Xu, Ningzhi, Liang, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659289/
https://www.ncbi.nlm.nih.gov/pubmed/31345225
http://dx.doi.org/10.1186/s12964-019-0392-9