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An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

BACKGROUND: There is mounting evidence that our environment and lifestyle has an impact on epigenetic regulatory mechanisms, such as DNA methylation. It has been suggested that these molecular processes may mediate the effect of risk factors on disease susceptibility, although evidence in this regar...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G, Richmond, Rebecca C, North, Teri-Louise, Hemani, Gibran, Davey Smith, George, Sharp, Gemma C, Relton, Caroline L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659375/
https://www.ncbi.nlm.nih.gov/pubmed/31257439
http://dx.doi.org/10.1093/ije/dyz119